Machine learning has shown promise in facial dysmorphology, where characteristic facial features provide diagnostic clues for rare genetic disorders. GestaltMatcher, a leading framework in this field, has demonstrated clinical utility across multiple studies, but its reliance on centralized datasets limits further development, as patient data are siloed across institutions and subject to strict privacy regulations. We introduce a federated GestaltMatcher service based on a cross-silo horizontal federated learning framework, which allows hospitals to collaboratively train a global ensemble feature extractor without sharing patient images. Patient data are mapped into a shared latent space, and a privacy-preserving kernel matrix computation framework enables syndrome inference and discovery while safeguarding confidentiality. New participants can directly benefit from and contribute to the system by adopting the global feature extractor and kernel configuration from previous training rounds. Experiments show that the federated service retains over 90% of centralized performance and remains robust to both varying silo numbers and heterogeneous data distributions.

ACCEPTED IN: IEEE NETWORKING LETTERS 1 Network Resource Optimization for ML-Based UA V Condition Monitoring with Vibration Analysis Alexandre Gemayel, Dimitrios Michael Manias, and Abdallah Shami Abstract --As smart cities begin to materialize, the role of Unmanned Aerial V ehicles (UA Vs) and their reliability becomes increasingly important. One aspect of reliability relates to Condition Monitoring (CM), where Machine Learning (ML) models are leveraged to identify abnormal and adverse conditions. Given the resource-constrained nature of next-generation edge networks, the utilization of precious network resources must be minimized. This work explores the optimization of network resources for ML-based UA V CM frameworks. The developed framework uses experimental data and varies the feature extraction aggregation interval to optimize ML model selection. Additionally, by leveraging dimensionality reduction techniques, there is a 99.9% reduction in network resource consumption. I NTRODUCTION E MERGING Unmanned Aerial V ehicle (UA V) applications, such as Smart Cities, have highlighted the necessity of real-time Condition Monitoring (CM) through Anomaly Detection (AD) and health analytics to ensure operational safety and integrity [1].

E-health allows smart devices and medical institutions to collaboratively collect patients' data, which is trained by Artificial Intelligence (AI) technologies to help doctors make diagnosis. By allowing multiple devices to train models collaboratively, federated learning is a promising solution to address the communication and privacy issues in e-health. However, applying federated learning in e-health faces many challenges. First, medical data is both horizontally and vertically partitioned. Since single Horizontal Federated Learning (HFL) or Vertical Federated Learning (VFL) techniques cannot deal with both types of data partitioning, directly applying them may consume excessive communication cost due to transmitting a part of raw data when requiring high modeling accuracy. Second, a naive combination of HFL and VFL has limitations including low training efficiency, unsound convergence analysis, and lack of parameter tuning strategies. In this paper, we provide a thorough study on an effective integration of HFL and VFL, to achieve communication efficiency and overcome the above limitations when data is both horizontally and vertically partitioned. Specifically, we propose a hybrid federated learning framework with one intermediate result exchange and two aggregation phases. Based on this framework, we develop a Hybrid Stochastic Gradient Descent (HSGD) algorithm to train models. Then, we theoretically analyze the convergence upper bound of the proposed algorithm. Using the convergence results, we design adaptive strategies to adjust the training parameters and shrink the size of transmitted data. Experimental results validate that the proposed HSGD algorithm can achieve the desired accuracy while reducing communication cost, and they also verify the effectiveness of the adaptive strategies.

Federated learning (FL) is a powerful distributed machine learning framework where a server aggregates models trained by different clients without accessing their private data. Hierarchical FL, with a client-edge-cloud aggregation hierarchy, can effectively leverage both the cloud server's access to many clients' data and the edge servers' closeness to the clients to achieve a high communication efficiency. Neural network quantization can further reduce the communication overhead during model uploading. To fully exploit the advantages of hierarchical FL, an accurate convergence analysis with respect to the key system parameters is needed. Unfortunately, existing analysis is loose and does not consider model quantization. In this paper, we derive a tighter convergence bound for hierarchical FL with quantization. The convergence result leads to practical guidelines for important design problems such as the client-edge aggregation and edge-client association strategies. Based on the obtained analytical results, we optimize the two aggregation intervals and show that the client-edge aggregation interval should slowly decay while the edge-cloud aggregation interval needs to adapt to the ratio of the client-edge and edge-cloud propagation delay. Simulation results shall verify the design guidelines and demonstrate the effectiveness of the proposed aggregation strategy.